Tuyển tập báo cáo các nghiên cứu khoa học quốc tế ngành y học dành cho các bạn tham khảo đề tài: Evaluation of the microbial growth response to inorganic nanoparticles | Journal of Nanobiotechnology BioMed Central Research Open Access Evaluation of the microbial growth response to inorganic nanoparticles Darryl N Williams Sheryl H Ehrman and Tracey R Pulliam Holoman Address Department of Chemical and Biomolecular Engineering University of Maryland 2113 Building 090 College Park MD 20742 USA Email Darryl N Williams - dnwilli@ Sheryl H Ehrman - sehrman@ Tracey R Pulliam Holoman - tholoman@ Corresponding author Published 28 February 2006 Received 29 December 2004 _k A II n uÂ-7-7 - 11-1- - Accepted 28 February 2006 Journal of Nanobiotechnology2006 4 3 doi 1477-3155-4-3 This article is available from http content 4 1 3 2006Williams et al licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License http licenses by which permits unrestricted use distribution and reproduction in any medium provided the original work is properly cited. Abstract In order to enhance the utilization of inorganic nanoparticles in biological systems it is important to develop a fundamental understanding of the influence they have on cellular health and function. Experiments were conducted to test silica silica iron oxide and gold nanoparticles for their effects on the growth and activity of Escherichia coli E. coli . Transmission electron microscopy TEM and dynamic light scattering DLS were used to characterize the morphology and quantify size distribution of the nanoparticles respectively. TEM was also used to verify the interactions between composite iron oxide nanoparticles and E. coli. The results from DLS indicated that the inorganic nanoparticles formed small aggregates in the growth media. Growth studies measured the influence of the nanoparticles on cell proliferation at various concentrations showing that the growth of E. coli in media containing the nanoparticles indicated no overt signs of .
