Tuyển tập báo cáo các nghiên cứu khoa học quốc tế ngành y học dành cho các bạn tham khảo đề tài: Treatment of stasis dermatitis using aminaphtone: solated angioedema of the bowel due to C1 esterase inhibitor deficiency: a case report and review of literature. | Kothari et al. Journal of Medical Case Reports 2011 5 62 http content 5 1 62 JOURNAL OF MEDICAL CASE REPORTS CASE REPORT Open Access Isolated angioedema of the bowel due to C1 esterase inhibitor deficiency a case report and review of literature 1 1 2 1 3 1 Shivangi T Kothari Anish M Shah Deviprasad Botu Robert Spira Robert Greenblatt and Joseph Depasquale Abstract Introduction We report a rare classic case of isolated angioedema of the bowel due to C1-esterase inhibitor deficiency. It is a rare presentation and very few cases have been reported worldwide. Angioedema has been classified into three categories. Case presentation A 66-year-old Caucasian man presented with a ten-month history of episodic severe cramping abdominal pain associated with loose stools. A colonoscopy performed during an acute attack revealed nonspecific colitis. Computed tomography of the abdomen performed at the same time showed a thickened small bowel and ascending colon with a moderate amount of free fluid in the abdomen. Levels of C4 8 mg dL reference range 15 to 50 mg dL CH50 10 U mL reference range 29 to 45 U ml and C1 inhibitor 4 mg dL reference range 14 to 30 mg dL were all low supporting a diagnosis of acquired angioedema with isolated bowel involvement. Our patient s symptoms improved with antihistamine and supportive treatment. Conclusion In addition to a detailed comprehensive medical history laboratory data and imaging studies are required to confirm a diagnosis of angioedema due to C1 esterase inhibitor deficiency. Introduction The term angioedema describes a circumscribed edema of the skin gastrointestinal GI tract or respiratory tract. Classic hereditary angioedema HAE can be associated with quantitative type I or qualitative type II deficiency of C1 esterase inhibitor C1-INH which is caused by mutations in the C1-INH gene 1 . In classic HAE abdominal attacks are mostly characterized by pain vomiting and diarrhea but rarely occur in the absence of .
