Tuyển tập báo cáo các nghiên cứu khoa học quốc tế ngành y học dành cho các bạn tham khảo đề tài: Recurrent tibial intra-cortical osteosarcoma: a case report and review of the literature. | Arpornchayanon et al. Journal of Medical Case Reports 2011 5 93 http content 5 1 93 JOURNAL OF MEDICAL CASE REPORTS CASE REPORT Open Access Recurrent tibial intra-cortical osteosarcoma a case report and review of the literature Olarn Arpornchayanon1 Taninnit Leerapun1 Chate Sivasomboon2 Jongkolnee Settakorn3 Nantawit Sugandhavesa1 Dumnoensun Pruksakorn1 Abstract Introduction Intra-cortical osteosarcoma is the rarest subtype of osseous-producing tumor. Most reported cases present a low-grade histology with slow progression and good oncological control after adequate treatment. In this report we describe a case and review the literature to propose adequate treatment. Case presentation We present the case of a 21-year-old Thai woman who was thought to have an intra-cortical osteosarcoma of the right tibia. We performed a wide resection and reconstruction with bone transportation using an Ilizarov external fixator. The tumor recurred five years later at the same site with a similar histology. We performed a new resection and reconstruction by ankle arthrodesis with adjuvant chemotherapy. At the last follow-up she had remained active and free from disease for seven years. Conclusion This case report of recurrent intra-cortical osteosarcoma describes an atypical presentation. The low-grade histology adequate surgical margin and adjuvant chemotherapy of the recurrent lesion were favorable factors and our patient has remained free of any tumor recurrence. Introduction Intra-cortical osteosarcoma is a low-grade malignancy tumor of the cortical bone which typically does not extend into the intra-medullary and surrounding soft tissues. Only 18 cases have been reported in the literature and the most common sites are the tibia nine cases and the femur nine cases . The sex ratio of females to males is 5 13 and the median age is 19 years range nine to 43 years . Most cases present with slow progression and treatment results in good oncological control.
