Tuyển tập báo cáo các nghiên cứu khoa học quốc tế ngành y học dành cho các bạn tham khảo đề tài: Papillary renal cell carcinoma with metastatic laparoscopic port site and vaginal involvement: a case report. | Chuang et al. Journal of Medical Case Reports 2011 5 131 http content 5 1 131 JOURNAL OF MEDICAL CASE REPORTS CASE REPORT Open Access Papillary renal cell carcinoma with metastatic laparoscopic port site and vaginal involvement a case report Xue En Chuang1 Hwai Liang Loh2 Hong Gee Sim3 Kah Leng Fong4 and Min-Han Tan1 Abstract Introduction Laparoscopic port-site metastasis is a rare but well recognized outcome following surgery in urological cancers with its etiology not clearly understood. Additionally vaginal metastasis in clear cell renal cell carcinoma is rare and has not been previously reported in the setting of papillary renal cell carcinoma. Case presentation We present the case of a 71-year-old Chinese woman with metastatic type II papillary renal cell carcinoma with histologically verified vaginal involvement and a concurrent laparoscopic port-site metastasis. This was also associated with a unique constellation of widely disseminated metastatic sites which include a local relapse the peritoneum and the urethra. Conclusion Laparoscopic port-site metastases are associated with the presence of advanced cancer with multiple sites of metastasis. We hypothesize from the findings of our report and background data that this phenomenon is more likely to be related to tumor factors rather than operative factors. We also present what is to the best of our knowledge the first reported case in the literature of vaginal and urethral metastasis and the second reported case of laparoscopic port-site recurrence. Background Renal cell carcinoma is well known for its ability to metastasize widely to nearly every organ in the body. While vaginal metastases are very rare with the mode of spread still currently obscure it is critical to differentiate these metastases from primary vaginal carcinomas which are rare and constitute approximately 2 of all malignant neoplasms of the female genital tract 1 . To date all renal cell carcinoma RCC metastases
