Tuyển tập báo cáo các nghiên cứu khoa học quốc tế ngành y học dành cho các bạn tham khảo đề tài: Coexistence of a colon carcinoma with two distinct renal cell carcinomas: a case report. | Papalampros et al. Journal of Medical Case Reports 2011 5 134 http content 5 1 134 JOURNALOF medical Ur Case REPORTS CASE REPORT Open Access Coexistence of a colon carcinoma with two distinct renal cell carcinomas a case report 1 1 1 2 Alexandros E Papalampros Athanasios S Petrou Eleftherios I Mantonakis Konstantinos I Evangelou Lambros A Giannopoulos1 Georgios G Marinos1 and Athanasios L Giannopoulos1 Abstract Introduction We present the case of a patient with two tumors in his left kidney and a synchronous colon cancer. While coexisting tumors have been previously described in the same kidney or the kidney and other organs or the colon and other organs to the best of our knowledge no such concurrency of three primary tumors has been reported in the literature to date. Case presentation A 72-year-old man of Greek nationality presenting with pain in the right hypochondrium underwent a series of examinations that revealed gallstones a tumor in the hepatic flexure of the colon and an additional tumor in the upper pole of the left kidney. He was subjected to a right hemicolectomy left nephrectomy and cholecystectomy and his postoperative course was uneventful. Histopathology examinations showed a mucinous colon adenocarcinoma plus two tumors in the left kidney a papillary renal cell carcinoma and a chromophobe renal cell carcinoma. Conclusion This case underlines the need to routinely scan patients pre-operatively in order to exclude coexisting tumors especially asymptomatic renal tumors in patients with colorectal cancer and additionally to screen concurrent tumors genetically in order to detect putative common genetic alterations. Introduction Synchronous multiple primary tumors are relatively rare. The etiology and pathogenesis of such multiple tumors remain unclear. It has been hypothesized that concurrent tumors can arise from tissues with similar embryological origin when they are simultaneously affected by factors such as carcinogens
