Tuyển tập báo cáo các nghiên cứu khoa học quốc tế ngành y học dành cho các bạn tham khảo đề tài: Corneal melting after collagen cross-linking for keratoconus: a case report. | Labiris et al. Journal of Medical Case Reports 2011 5 152 http content 5 1 152 JOURNAL OF MEDICAL CASE REPORTS CASE REPORT Open Access Corneal melting after collagen cross-linking for keratoconus a case report 12 1 1 3 Georgios Labiris Eleni Kaloghianni Stavrenia Koukoula Athanassios Zissimopoulos and Vassilios P Kozobolis1 2 Abstract Introduction Corneal collagen cross-linking is a rather new technique that uses riboflavin and ultraviolet A light for collagen fiber stabilization in keratoconus corneas. Other than reversible side effects the preliminary results of corneal collagen cross-linking studies suggest that it is a rather safe technique. In this report we demonstrate a case of corneal melting after corneal collagen cross-linking for keratoconus corneas associated with an acute inflammatory response. Case presentation A 23-year-old Caucasian man with keratoconus cornea stage 1 to 2 underwent uneventful corneal collagen cross-linking treatment according to the Dresden protocol. The next day the patient had intense photophobia watering and redness of the eye and his visual acuity was limited to counting fingers. Slit lamp biomicroscopy revealed severe corneal haze accompanied by non-specific endothelial precipitates following an acute inflammatory response. Mild inflammation could be detected in the anterior chamber. Moreover the re-epithelialization process could barely be detected. His corneal state gradually deteriorated resulting in descemetocele and finally perforation. Conclusion In this report we present a case of a patient with corneal melting after standard corneal collagen cross-linking treatment for keratoconus corneas following an acute inflammatory response. Despite modifying postoperative treatment elaboration of all apparent associated causes by the treating physicians and undergoing extensive laboratory testing the patient developed descemetocele which led to perforation. Our report suggests that further research is
