Tuyển tập báo cáo các nghiên cứu khoa học quốc tế ngành y học dành cho các bạn tham khảo đề tài: Magnetic resonance imaging findings within the posterior and lateral columns of the spinal cord extended from the medulla oblongata to the thoracic spine in a woman with subacute combined degeneration without hematologic disorders: a case report and review of the literature. | Rabhi et al. Journal of Medical Case Reports 2011 5 166 http content 5 1 166 WV journalof medical l rCASE REPORTS CASE REPORT Open Access Magnetic resonance imaging findings within the posterior and lateral columns of the spinal cord extended from the medulla oblongata to the thoracic spine in a woman with subacute combined degeneration without hematologic disorders a case report and review of the literature 1 2 1 3 2 1 Samira Rabhi Mustapha Maaroufi Hajar Khibri Faouzy Belahsen Siham Tizniti Rhizlane Berrady and Wafaa Bono1 Abstract Introduction Subacute combined degeneration of the spinal cord is a rare cause of demyelination of the dorsal and lateral columns of the spinal cord and is a neurological complication of vitamin B12 deficiency. Subacute combined degeneration without anemia or macrocytosis is rare. Case presentation We present a case of cobalamin deficiency in a 29-year-old Moroccan woman who presented with subacute combined degeneration without evidence of anemia or macrocytosis. Magnetic resonance imaging of the spinal cord demonstrated abnormal hyperintense signal changes on T2-weighted imaging of the posterior and lateral columns from the medulla oblongata to the thoracic spine. A diagnosis of subacute combined degeneration of the spinal cord was considered and confirmed by low serum cobalamin. The patient was treated with vitamin B12 supplements and showed improvement in her clinical symptoms. Conclusion Physicians should diagnose subacute combined degeneration in patients early by having a high index of suspicion and using diagnostic tools such as magnetic resonance imaging. Introduction Vitamin B12 deficiency usually presents with various hematological gastrointestinal and neuropsychiatric manifestations. Commonly seen neuropsychiatric manifestations include myelopathy neuropathy dementia neuropsychiatric abnormalities and rarely optic nerve atrophy. Subacute combined degeneration SCD of the spinal cord is an uncommon
