báo cáo khoa học: " Duodenal gastrointestinal stromal tumor resembling a pancreatic neuroendocrine tumor in a patient with neurofibromatosis type I (von Recklinghausen’s disease): a case report"

Tuyển tập báo cáo các nghiên cứu khoa học quốc tế ngành y học dành cho các bạn tham khảo đề tài: Duodenal gastrointestinal stromal tumor resembling a pancreatic neuroendocrine tumor in a patient with neurofibromatosis type I (von Recklinghausen’s disease): a case report | Ohtake et al. Journal of Medical Case Reports 2010 4 302 http content 4 1 302 jAg JOURNALOF medical ÌỤr case REPORTS CASE REPORT Open Access Duodenal gastrointestinal stromal tumor resembling a pancreatic neuroendocrine tumor in a patient with neurofibromatosis type I von Recklinghausen s disease a case report 1 1 1 12 3 Shinji Ohtake Noritoshi Kobayashi Shingo Kato Kensuke Kubota Itaru Endo Yoshiaki Inayama Atsushi Nakajima1 Abstract Introduction Gastrointestinal stromal tumor is the most frequent nonepithelial tumor found in the gastrointestinal tract. One important clinical problem is that gastrointestinal stromal tumors especially the extramural growth type can be difficult to distinguish from other organ tumors. The case of a patient with an extramural gastrointestinal stromal tumor of the duodenum that mimicked a pancreatic head tumor has previously been reported. Here we report a rare case of a patient with a duodenal gastrointestinal stromal tumor with extramural growth that mimicked a pancreatic neuroendocrine tumor. In this case the gastrointestinal stromal tumor was also associated with neurofibromatosis type 1 also known as von Recklinghausen s disease . To the best of our knowledge this is the first report to describe the case of a patient with a duodenal gastrointestinal stromal tumor with neurofibromatosis type 1 in which the radiological findings resembled those of a pancreatic neuroendocrine tumor. Case presentation A 60-year-old Japanese woman with a history of neurofibromatosis type 1 was admitted to our hospital for the treatment of a tumor of her pancreas. She had no symptoms but an abdominal ultrasonography screening examination had revealed a hypoechoic mass in the head of her pancreas. Laboratory data including tumor markers were within the normal ranges and her insulin and glucagon levels were also within the normal ranges. However her plasma gastrin level was elevated at 580 pg mL 30 to 150 pg mL . A computed .

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