Tuyển tập báo cáo các nghiên cứu khoa học quốc tế ngành y học dành cho các bạn tham khảo đề tài: Extramedullary hematopoiesis presenting as a compressive cord and cerebral lesion in a patient without a significant hematologic disorder: a case report | Seddighi and Seddighi Journal of Medical Case Reports 2010 4 319 http content 4 1 319 JOURNALOF medical ÌỤr case REPORTS CASE REPORT Open Access Extramedullary hematopoiesis presenting as a compressive cord and cerebral lesion in a patient without a significant hematologic disorder a case report Amir Saied Seddighi1 3 Afsoun Seddighi2 3 Abstract Introduction Intracranial or spinal compressive lesions due to extramedullary hematopoiesis have been reported in the medical literature. Most of the reported cases are extradural lesions or on rare occasions foci within another neoplasm such as hemangioblastoma meningioma or pilocytic astrocytoma. Often these cases occur in patients with an underlying hematological disorder such as acute myelogenic leukemia myelofibrosis or other myelodysplastic syndromes. Such lesions have also been reported in thalassemia major. Case presentation We report the case of a 43-year-old Iranian woman in whom extramedullary hematopoiesis presented as a compressive cord lesion and then later as an intracranial lesion. Conclusions To the best of our knowledge we document the first reported case of sacral lumbar thoracic and cranial involvement in the same patient with extramedullary hematopoiesis which seems both rare and remarkable. Introduction Intracranial or spinal involvement manifesting as epidural lesions due to extramedullary hematopoiesis EMH is rare. The intracranial lesions are also reported as foci within another intracranial neoplasm such as hemangioblastoma meningioma or pilocytic astrocytoma 1 2 . Extramedullary hematoopoiesis usually occurs in patients with a significant hematologic disorder like acute myelogenic leukemia AML myelofibrosis MF myelodysplastic syndromes or thalassemia major 1-3 . Prior to our case report and to the best of our knowledge there has been no report of such a problem presenting as compressive spinal and cranial lesions in the same patient without a significant hematologic .
