Tuyển tập báo cáo các nghiên cứu khoa học quốc tế ngành y học dành cho các bạn tham khảo đề tài: Fulminant necrotizing fasciitis following the use of herbal concoction: a case report | Adigun et al. Journal of Medical Case Reports 2010 4 326 http content 4 1 326 JOURNALOF medical ÌỤr case REPORTS CASE REPORT Open Access Fulminant necrotizing fasciitis following the use of herbal concoction a case report Ismaila A Adigun1 2 Abdulrasheed A Nasir 2 Adebiyi B Aderibigbe2 Abstract Introduction Necrotizing fasciitis is a rare and life-threatening rapidly progressive soft tissue infection. A fulminant case could involve muscle and bone. Necrotizing fasciitis after corticosteroid therapy and intramuscular injection of non-steroidal anti-inflammatory drugs has been reported. We present a case of fulminant necrotizing fasciitis occurring in a patient who used a herbal concoction to treat a chronic leg ulcer. Case presentation A 20-year-old Ibo woman from Nigeria presented with a three-year history of recurrent chronic ulcer of the right leg. She started applying a herbal concoction to dress the wound two weeks prior to presentation. This resulted in rapidly progressive soft tissue necrosis that spread from the soft tissue to the bone despite aggressive emergency debridement. As a result she underwent above-knee amputation. Conclusion The herbal concoction used is toxic and can initiate and exacerbate necrotizing fasciitis. Its use for wound dressing should be discouraged. Introduction Necrotizing fasciitis NF is a rare but fatal rapidly progressive soft tissue infection which is characterized by widespread necrosis of the superficial fascia and the subcutaneous fat. NF spreads along the fascia plane usually sparing surface skin and the muscle but fulminating cases can affect the muscle. NF is associated with high mortality and long-term morbidity 1 2 . Early clinical suspicion of necrotizing fasciitis is crucial because patient survival is inversely related to the time between the onset of infection and the initiation of appropriate therapy 1 . Fulminating necrotizing fasciitis after corticosteroid therapy 3 and intramuscular .
