Tuyển tập báo cáo các nghiên cứu khoa học quốc tế ngành y học dành cho các bạn tham khảo đề tài: Concurrent breast stroma sarcoma and breast carcinoma: a case report | de Mello et al. Journal of Medical Case Reports 2010 4 414 http content 4 1 414 P vL JOURNALOF medical LrCASE REPORTS CASE REPORT Open Access Concurrent breast stroma sarcoma and breast carcinoma a case report 13 2 111 Ramon Andrade de Mello Paulo Figueiredo Mariela Marques Gabriela Sousa Teresa Carvalho Helena Gervásio1 Abstract Introduction Breast cancer is one of the most important health problems in the world and affects a great number of women over the entire globe. This group of tumors rarely presents as bilateral disease and when it does happen normally occurs within the same histological type. We report a rare case of concurrent bilateral breast cancer with two different histology types a breast carcinoma and a breast sarcoma in a 42-year-old woman referred to our hospital. Case presentation A 42-year-old Caucasian woman admitted to our institute in August 1999 presented with a nodule in the left breast of X cm and in the right breast one of cm suspected of malignancy and with a clinically negative armpit. Biopsies had revealed invasive mammary carcinoma right breast and sarcoma left breast . She was submitted to bilateral modified radical mastectomy. A histological study showed an invasive mammary carcinoma degree II lobular pleomorphic type with invasion of seven of the 19 excised axillary nodes in the right breast and in the left breast a sarcoma of the mammary stroma for which the immunohistochemistry study was negative for epithelial biomarkers and positive for vimentin. Later she was submitted for chemotherapy six cycles of 75 mg m2 5-fluorouracil epirubicin and cyclophosphamide followed by radiotherapy of the thoracic wall and axillary nodes on the left. Hormone receptors were positive in the tumor of the right breast and tamoxifen 20 mg was prescribed on a daily basis five years followed by letrozole mg also daily five years . She presented no sign of negative evolution in the last consultation. Conclusion
