Pathophysiology Review - part 10

Aspergillus là một khuôn mẫu được tìm thấy trong vật chất hữu cơ phân hủy hoặc phân hủy thực vật, đất, bụi hộ gia đình, vật liệu xây dựng, cây cảnh, thực phẩm, và nước. Về cơ bản, loại mốc này ở khắp mọi nơi! Nó là tác nhân gây bệnh của aspergillosis. | e142 MARLENE HURST Hurst Reviews Pathophysiology Review If I were your teacher I would test you on . . . Most common cause of fungal meningitis. Clients at risk immunocompromised clients such as those with cancer Hodgkin s disease or HIV AIDS and those receiving longterm steroid therapy remember long-term steroid therapy leads to immunosuppression . Aspergillosis What is it Aspergillus is a mold found in organic decaying matter or decomposing plant matter soil household dust building materials ornamental plants food and water. Essentially this mold is everywhere It is the causative agent of aspergillosis. Causes and signs and symptoms Table 20-33 shows the cause of infection and the associated signs and symptoms. Table 20-33 Causes Signs and symptoms Inhalation of Aspergillus can cause Shortness of breath related symptoms of asthma to bronchospasm Aspergillus can grow in the lung to Cough the extent of forming a ball aspergilloma Fever requiring surgical removal Sinus trouble Severely immunocompromised clients such as those with very advanced AIDS are at risk for pneumonia and systemic illness see Fig. 20-10 Figure 20-10. Aspergillus an opportunistic fungus. Photo generously provided by the CDC. Source Created by author from References 1 and 2. Quickie tests and treatments Tests include Chest x-ray to show aspergilloma fungal ball . CHAPTER 20 Infectious Diseases e143 Computed tomography CT scan of the chest. Biopsy the diagnostic test of choice. Sputum cultures are not reliable. Treatment includes Voriconazole antifungal . Amphotericin B antifungal . What can harm my client During construction projects this mold has been known to be released causing the death of immunocompromised clients. Bone marrow transplant clients have almost zero immunity. If construction occurs near their unit they can breathe in the released mold which ultimately causes death. Opening a client s window can harm the client especially if there is a construction project going on outside of .

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