Tham khảo luận văn - đề án 'báo cáo y học: " a neonate with left pulmonary artery thrombosis and left lung hypoplasia: a case report"', luận văn - báo cáo phục vụ nhu cầu học tập, nghiên cứu và làm việc hiệu quả | ElHassan et al. Journal of Medical Case Reports 2010 4 284 http content 4 1 284 jAl JOURNALOF medical ÌỤr case REPORTS CASE REPORT Open Access A neonate with left pulmonary artery thrombosis and left lung hypoplasia a case report 1 1 2 3 1 Nahed O ElHassan Christi Sproles Ritu Sachdeva SadafT Bhutta Joanne S Szabo Abstract Introduction Spontaneous intrauterine arterial thrombosis and congenital pulmonary hypoplasia are rare conditions and have not been reported to occur together. The literature rather includes two reports of babies with neonatal pulmonary artery occlusion and post-infarction cysts of the lungs. Case presentation We report a case of a live Caucasian male newborn with left lung hypoplasia that occurred in association with left pulmonary artery thrombosis. Despite a critical neonatal course including extracorporeal membrane oxygenation this infant is alive and well at 18 months of age without any neurodevelopmental sequelae or reactive airway disease. Conclusion This association suggests the possibility of an intrauterine vascular event between the fifth and eighth weeks of gestation during early pulmonary artery and lung development. Introduction The prevalence of symptomatic neonatal arterial thrombosis is approximately 1 in 40 000 births with 90 of cases linked to indwelling intra-arterial catheters 1-4 . Other risk factors are sepsis polycythemia maternal diabetes asphyxia and inherited thrombophilias 1 3 4 . Very few cases of spontaneous neonatal arterial thrombosis have ever been described 3 4 . Although congenital pulmonary hypoplasia can be idiopathic it is most commonly associated with conditions that reduce the intrathoracic space 5 . A limited number of reports exist of neonates with congenital pulmonary hypoplasia and no clear evidence of fetal chest compression 5-7 . Two previous reports exist in the literature of neonates with congenital left pulmonary occlusion and postinfarction cysts of the lung 8 9 . We .
