Tuyển tập báo cáo các nghiên cứu khoa học quốc tế ngành y học dành cho các bạn tham khảo đề tài: Modulation of mu rhythm desynchronization during motor imagery by transcranial direct current stimulation | Matsumoto et al. Journal of NeuroEngineering and Rehabilitation 2010 7 27 http content 7 1 27 J NER JOURNAL OF NEUROENGINEERING AND REHABILITATION RESEARCH Open Access Modulation of mu rhythm desynchronization during motor imagery by transcranial direct current stimulation Jun Matsumoto41 Toshiyuki Fujiwara 42 Osamu Takahashi3 Meigen Liu 2 Akio Kimura4 and Junichi Ushiba5 Abstract Background The mu event-related desynchronization ERD is supposed to reflect motor preparation and appear during motor imagery. The aim of this study is to examine the modulation of ERD with transcranial direct current stimulation tDCS . Methods Six healthy subjects were asked to imagine their right hand grasping something after receiving a visual cue. Electroencephalograms EEGs were recorded near the left M1. ERD of the mu rhythm mu ERD by right hand motor imagery was measured. tDCS 10 min 1 mA was used to modulate the cortical excitability of M1. Anodal cathodal and sham tDCS were tested in each subject with a randomized sequence on different days. Each condition was separated from the preceding one by more than 1 week in the same subject. Before and after tDCS mu ERD was assessed. The motor thresholds MT of the left M1 were also measured with transcranial magnetic stimulation. Results Mu ERD significantly increased after anodal stimulation whereas it significantly decreased after cathodal stimulation. There was a significant correlation between mu ERD and MT. Conclusions Opposing effects on mu ERD based on the orientation of the stimulation suggest that mu ERD is affected by cortical excitability. Background Mu rhythm is a spontaneous characteristic feature of the electroencephalogram EEG magnetoencep halogram MEG pattern that has 8-13 Hz activities that appear maximally over the central rolandic or sensorimotor area during a relaxed state. Mu rhythm is suggested to be present in 50-100 of healthy subjects 1 and is generally accepted as the idling rhythm .
