Tuyển tập báo cáo các nghiên cứu khoa học quốc tế ngành y học dành cho các bạn tham khảo đề tài: Testing the potential of a virtual reality neurorehabilitation system during performance of observation, imagery and imitation of motor actions recorded by wireless functional nearinfrared | Holper et al. Journal of NeuroEngineering and Rehabilitation 2010 7 57 http content 7 1 57 Hill JOURNAL OF NEUROENGINEERING NCR AND REHABILITATION RESEARCH Open Access Testing the potential of a virtual reality neurorehabilitation system during performance of observation imagery and imitation of motor actions recorded by wireless functional nearinfrared spectroscopy fNIRS 13 1 2 2 1 Lisa Holper1 Thomas Muehlemann 1 Felix Scholkmann Kynan Eng Daniel Kiper Martin Wolf Abstract Background Several neurorehabilitation strategies have been introduced over the last decade based on the so-called simulation hypothesis. This hypothesis states that a neural network located in primary and secondary motor areas is activated not only during overt motor execution but also during observation or imagery of the same motor action. Based on this hypothesis we investigated the combination of a virtual reality VR based neurorehabilitation system together with a wireless functional near infrared spectroscopy fNIRS instrument. This combination is particularly appealing from a rehabilitation perspective as it may allow minimally constrained monitoring during neurorehabilitative training. Methods fNIRS was applied over F3 of healthy subjects during task performance in a virtual reality VR environment 1 unilateral group N 15 contralateral recording during observation motor imagery observation motor imagery and imitation of a grasping task performed by a virtual limb first-person perspective view using the right hand 2 bilateral group N 8 bilateral recording during observation and imitation of the same task using the right and left hand alternately. Results In the unilateral group significant within-condition oxy-hemoglobin concentration A O2Hb changes mean SD pmol l were found for motor imagery pmol l and imitation pmol l . In addition the bilateral group showed a significant within-condition A O2Hb change for observation .
