Tuyển tập báo cáo các nghiên cứu khoa học quốc tế ngành y học dành cho các bạn tham khảo đề tài: Atrial and placental melanoma metastasis: a case report and literature review. | Journal of Medical Case Reports BioMed Central Open Access Case report Atrial and placental melanoma metastasis a case report and literature review Pradeep Lakshminarayana 1 Sarah Danson1 Kim Suvarna2 and Barry Hancock1 Address Department of Clinical Oncology Weston Park Hospital Whitham Road Sheffield S10 2SJ UK and 2Department of Histopathology Northern General Hospital Herries Road Sheffield S5 7AU UK Email Pradeep Lakshminarayana - drpradeephl@ Sarah Danson - Kim Suvarna - Barry Hancock - Corresponding author Published 14 May 2007 Received 7 April 2007 Journal of Medical Case Reports 2007 1 21 doi 1752-1947-1-21 Accepted 14 May 2007 This article is available from http content 1 1 21 2007 Lakshminarayana et al licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License http licenses by which permits unrestricted use distribution and reproduction in any medium provided the original work is properly cited. Abstract Malignant melanoma can metastasize to virtually any organ of the body. The aggressiveness is determined by the primary site depth of dermal invasion presence or absence of ulceration lymphovascular infiltration and regional lymph node involvement. We report a case of a pregnant woman with a previous history of stage 3 melanoma who presented with cardiac metastasis and placental melanoma infiltration. A review of literature on cardiac and placental involvement of melanoma is also provided. Background Malignant melanoma is considered to be a highly aggressive cancer. Post mortem studies have shown that melanoma can metastasize to any organ of the body with 50 of the patients found to have cardiac involvement 1 . However only 2 of patients with metastatic melanoma to the heart are diagnosed antemortem 2 as most patients do not have any .
