Tuyển tập báo cáo các nghiên cứu khoa học quốc tế ngành y học dành cho các bạn tham khảo đề tài: Mycobacterial immune reconstitution inflammatory syndrome in HIV-1 infection after antiretroviral therapy is associated with deregulated specific T-cell responses: Beneficial effect of IL-2 and GM-CSF immunotherapy. | Journal of Immune Based Therapies and Vaccines Original research BioMed Central Open Access Mycobacterial immune reconstitution inflammatory syndrome in HIV-1 infection after antiretroviral therapy is associated with deregulated specific T-cell responses Beneficial effect of IL-2 and GM-CSF immunotherapy A Pires1 M Nelson2 AL Pozniak2 M Fisher3 B Gazzard2 F Gotch1 and N Imami 1 Address Department of Immunology Imperial College London Chelsea and Westminster Hospital 369 Fulham Road London. UK 2Department of HIV GU Medicine Chelsea and Westminster Hospital 369 Fulham Road London UK and 3Department of HIV GU Medicine Royal Sussex County Hospital Brighton UK Email A Pires - M Nelson - AL Pozniak - M Fisher - B Gazzard - F Gotch - N Imami - Corresponding author Published 25 September 2005 Received 06 April 2004 Accepted 25 September 2005 Journal of Immune Based Therapies and Vaccines 2005 3 7 doi 1476- 8518-3-7 This article is available from http content 3 1 7 2005 Pires et al licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License http licenses by which permits unrestricted use distribution and reproduction in any medium provided the original work is properly cited. Abstract Background With the advent of antiretroviral therapy ART cases of immune reconstitution inflammatory syndrome IRIS have increasingly been reported. IRIS usually occurs in individuals with a rapidly rising CD4 T-cell count or percentage upon initiation of ART who develop a deregulated immune response to infection with or without reactivation of opportunistic organisms. Here we evaluated rises in absolute CD4 T-cells and specific CD4 T-cell responses in 4 HIV-1 individuals presenting
