Tuyển tập báo cáo các nghiên cứu khoa học quốc tế ngành y học dành cho các bạn tham khảo đề tài:Extragonadal germ cell tumor presenting in a woman with systemic lupus erythematosus: a case report | Shahrir et al. Journal of Medical Case Reports 2010 4 97 http content 4 1 97 jAg JOURNALOF medical ÌỤr case REPORTS CASE REPORT Open Access Extragonadal germ cell tumor presenting in a woman with systemic lupus erythematosus a case report Mohd Shahrir Abdul Halim Soehardy Zainudin Rozita Mohamad Loo C Yuen Rashidi Saidin Norella Kong Abstract Introduction Germ cell tumor of the pituitary gland is a very rare occurrence. Case presentation We describe the case of a 28-year-old Malaysian Malay woman with lupus nephritis who complained of a three month headache and blurring of vision. She was found to have a pituitary mass which was later proven to be a germ cell tumor. As of writing this case report her disease is in remission. Conclusion The disruption of the pituitary gonad axis could affect the disease activity by reducing immunoregulatory control. Introduction Germ cell tumor of the pituitary gland is a very rare occurrence. This case report describes a 28-year-old Malaysian Malay woman with lupus nephritis who complained of headache and blurring of vision. She was later found to have a pituitary germ cell tumor. Pituitary germ cell tumor is considered as a type of extragonadal germ cell tumor. They represent 5 of germ cell tumors and typically arise in midline locations. The specific location of the tumor varies with the patient s age 1 . The most common sites of origin in adults are the anterior mediastinum the retroperito-neum and the pineal and suprasellar regions of the brain. Meanwhile in infants and young children the sacrococcyx is the most common site of extragonadal germ cell tumors followed by intracranial sites 2 . In contrast to primary gonadal germ cell tumors the only known risk factor for extragonadal germ cell tumors is the Klinefelter syndrome 47XXY which is associated with mediastinal nonseminomatous germ cell tumors 3 . The age of onset site of origin and histologic type of the tumor are important distinguishing .
