Tuyển tập báo cáo các nghiên cứu khoa học quốc tế ngành y học dành cho các bạn tham khảo đề tài: A severe case of erythrodermic psoriasis associated with advanced nail and joint manifestations: a case report. | Teran et al. Journal of Medical Case Reports 2010 4 179 http content 4 1 179 jA CASE REPORTS CASE REPORT Open Access A severe case of erythrodermic psoriasis associated with advanced nail and joint manifestations a case report Carlos G Teran Carlos N Teran-Escalera and Carola Balderrama Abstract Introduction Erythrodermic psoriasis is a rare generalized clinical presentation of psoriasis in children and adults. Its systemic involvement and a diverse range of clinical findings in the joint and nails are commonly described. A high index of suspicion and an exhaustive differential diagnosis involving other causes of erythroderma should be initially considered. Case presentation We present the case of a 9-year-old native Hispanic girl with severe erythrodermic psoriasis associated with uncommon advanced nail and joint manifestations. Our patient showed an excellent response to methotrexate medication. Conclusion This case shows clinical features not commonly described or reported in severe cases of erythrodermic psoriasis including severe and rare nail and arthritic findings in a pediatric scenario. Introduction Erythrodermic psoriasis is considered a rare clinical presentation. It may arise from any type of psoriasis and occurs in adults children and babies 1 . It is well known that trauma infections and drugs such as lithium anti-malarials trimethoprim and sulfamethoxazole as well as environmental psychological and metabolic factors can trigger psoriasis and the erythrodermic form of the disease 2 3 . The generalized manifestations of the disease are erythema edema desquamation and systemic compromise fever dehydration malaise and malnutrition 4 . This disease ranges from mild to severe as in the case of our patient Nail malformations ranging from mild pitting with yellowish discoloration to severe onychodystrophy are seen in all types of the disease. These symptoms are more pronounced in the fingernails than in the .
