Tuyển tập báo cáo các nghiên cứu khoa học quốc tế ngành y học dành cho các bạn tham khảo đề tài: Non-small cell lung cancer presenting with choroidal metastasis as first sign and showing good response to chemotherapy alone: a case report. | Singh et al. Journal of Medical Case Reports 2010 4 185 http content 4 1 185 jAl JOURNALOF medical ÌỤr case REPORTS CASE REPORT Open Access Non-small cell lung cancer presenting with choroidal metastasis as first sign and showing good response to chemotherapy alone a case report A t 1 n i c n Q wWP iru Cirsrsls2 l .irn .ì Cnhrsi3 Proafx chi ilzln3 ilzsc CK ilzln4 ixlirr lrrckr I Pnj-il-1 Abllisiiek Singh rarul Singh Kamal sain II Fleecy Shukla Vikas Shukla INIlUUsI 1 K rant Abstract Introduction Metastatic tumors are the most common Intra-ocular malignancies and choroid Is by far the most common site for Intra-ocular malignancies. Multiple foci are usually Involved and bilateral Involvement Is frequently seen. The primary sites for choroidal metastasis In decreasing order and by gender are breast lung unknown primary gastrointestinal and pancreas skin melanoma and other rare sources In females and lung unknown primary gastrointestinal and pancreas prostate kidney skin melanoma and other rare sources In males. Available treatment options are external beam radiotherapy and plaque radiotherapy while new methods like surgical resection transpupillary thermotherapy and intravitreal chemotherapy offer promises for the future. The use of chemotherapy alone for choroidal metastases Is not widely reported. Case presentation We report the case of a 50-year-old Indian man who had a unilateral solitary lesion In his right eye. He was found to have an adenocarcinoma of the lung with choroidal metastasis as the first presenting sign. There were no findings of metastasis Involving his contralateral eye. He was administered chemotherapy based on gemcitabine and carboplatin. He had significant progressive subjective and objective Improvement since his first chemotherapy. His current best corrected visual acuity Is 20 30 after six cycles of chemotherapy. Conclusions Chemotherapy alone can be used as an effective mode of treatment In patients who have .
