Tuyển tập báo cáo các nghiên cứu khoa học quốc tế ngành y học dành cho các bạn tham khảo đề tài: Data reporting standards: making the things we use better | Genome Medicine Commentary Data reporting standards making the things we use better John Quackenbush Address Department of Biostatisics and Computational Biology and Department of Cancer Biology Dana-Farber Cancer Institute and Department of Biostatisics 44 Binney Street Sm822 Boston MA 02115 USA. Email johnq@ Abstract Genomic data often persist far beyond the initial study in which they were generated. But the true value of the data is tied to their being both used and useful and the usefulness of the data relies intimately on how well annotated they are. While standards such as MIAME have been in existence for nearly a decade we cannot think that the problem is solved or that we can ignore the need to develop better more effective methods for capturing the essence of the meta-data that is ultimately required to guarantee utility of the data. There was a time when making one s data publicly available meant publishing the image of a gel as part of a manuscript. After all anyone else could look at the evidence in the picture judge the quality of the data and draw a conclusion about whether the data supported the conclusions presented in the manuscript. As DNA sequence data began to become more common in published research articles authors regularly included figures or tables that presented the base sequence they had determined and other scientists could use those data by manually transcribing the sequence and performing their own analysis. But as the complexity of sequence data grew and the scale of sequencing expanded with improvements in technology it quickly became obvious that other more systematic solutions were necessary. And hence was born GenBank and the other international sequence repositories. GenBank started at Los Alamos National Laboratory as little more than a research project on how to index and archive DNA sequence and quickly became an international resource and one of the major products of the National Library of Medicine and its
