báo cáo khoa học: " So what have data standards ever done for us? The view from metabolomics"

Tuyển tập báo cáo các nghiên cứu khoa học quốc tế ngành y học dành cho các bạn tham khảo đề tài: So what have data standards ever done for us? The view from metabolomics | Griffin and Steinbeck Genome Medicine 2010 2 38 http content 2 6 38 w Genome Medicine MUSINGS L__ So what have data standards ever done for us The view from metabolomics Julian L Griffin 1 2 3 and Christoph Steinbeck4 Abstract The standardization of reporting of data promises to revolutionize biology by allowing community access to data generated in laboratories across the globe. This approach has already influenced genomics and transcriptomics. Projects that have previously been viewed as being too big to implement can now be distributed across multiple sites. There are now public databases for gene sequences transcriptomic profiling and proteomic experiments. However progress in the metabolomic community has seemed to falter recently and whereas there are ontologies to describe the metadata for metabolomics there are still no central repositories for the datasets themselves. Here we examine some of the challenges and potential benefits of further efforts towards data standardization in metabolomics and metabonomics. Whatever the branch of genome science one is part of the need for data standards more specifically standardized ways to describe an experiment and central repositories for the huge multivariate datasets that researchers are now acquiring seem self-evident. The community needs to be able to reproduce analyses for key experiments and if the experimenter is satisfied with the quality of the data why should the data not be made available for all In many ways central repositories for data made the field of genome science accessible to the wider academic community with over 192 complete sequenced genomes now available for researchers to interrogate. Similarly moving from genome sequencing to functional genomics the Microarray Gene Expression Databases MGED society developed a community-wide agreement on Correspondence jlg40@ The Department of Biochemistry Tennis Court Road University of Cambridge Cambridge CB2 GA UK Full .

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