Predicting Chemical Toxicity and Fate - Section 1

Chemicals are able to bring about both desirable and undesirable effects on organisms to which they are exposed, and the actions of medicines and poisons and toxic agents have been recognized for thousands of years. As a result of industrialization, modern man and the environment is now exposed to increasing numbers of chemicals. Because of their potential hazard, there is an appreciation of the requirement to assess the effects of these chemicals. Since chemical structure was elucidated (for a very brief history see Table ), the relationship between chemical structure andHóa chất là có thể mang lại hiệu ứng mong muốn và không mong muốn. | Predicting Chemical Toxicity 2004 by CRC Press LLC Predicting Chemical Toxicity Mark . Cronin Liverpool John Moores University Liverpool England David J. Livingstone University of Portsmouth Portsmouth England CRC PRESS Boca Raton London New York Washington . 2004 by CRC Press LLC Library of Congress Cataloging-in-Publication Data Predicting chemical toxicity and fate edited by Mark . Cronin and David J. Livingstone. p. cm. Includes bibliographical references and index. ISBN 0-415-27180-0 alk. paper 1. Molecular toxicology. 2. Toxicological chemistry. 3. QSAR Biochemistry . I. Cronin Mark . II. Livingstone D. David . III. Title. 2004 dc22 2004043999 This book contains information obtained from authentic and highly regarded sources. Reprinted material is quoted with permission and sources are indicated. A wide variety of references are listed. Reasonable efforts have been made to publish reliable data and information but the author and the publisher cannot assume responsibility for the validity of all materials or for the consequences of their use. Neither this book nor any part may be reproduced or transmitted in any form or by any means electronic or mechanical including photocopying microfilming and recording or by any information storage or retrieval system without prior permission in writing from the publisher. All rights reserved. Authorization to photocopy items for internal or personal use or the personal or internal use of specific clients may be granted by CRC Press LLC provided that per page photocopied is paid directly to Copyright Clearance Center 222 Rosewood Drive Danvers MA 01923 USA. The fee code for users of the Transactional Reporting Service is ISBN 0-415-27180-0 04 . The fee is subject to change without notice. For organizations that have been granted a photocopy license by the CCC a separate system of payment has been arranged. The consent of CRC Press LLC does not extend to copying for general .

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