Cập nhật kiến nghị, phát triển trong một sự hợp tác giữa Hoa Kỳ và Canada, kết hợp ba loại giá trị: yêu cầu trung bình ước tính (EAR), trợ cấp chế độ ăn uống được đề nghị (RDA) và mức độ chấp nhận được tiêu thụ trên (UL). | 10 Rafaela M. Quiroga Unexpectedly there was a near doubling of mortality from 20 to 38 in both studies. A Brief Guide to Anti-Aging Supplements and Growth-Hormone-Releasing Nutrients for the Skin Updated recommendations developed in a collaboration between the United States and Canada incorporate three types of values the estimated average requirement EAR the recommended dietary allowance RDA and the tolerable upper intake level UL . Collectively these values are referred to as dietary reference intakes DRIs . EAR is the intake value that is estimated to meet the requirements of a defined indicator of adequacy in 50 of the population note that this means that the needs of 50 of the population are not being met . RDA is the dietary intake level that is sufficient to meet the nutrient requirements of nearly all individuals in the group. UL is not intended to be a recommended level of intake but represents the highest level of intake that is unlikely to have any adverse health effects in most individuals. It is important to note that the UL is not meant to apply to individuals receiving supplements under medical supervision and should not be used to limit doses investigated in clinical trials 42 . DRIs for antioxidant nutrients were developed by considering the roles of antioxidant nutrients in decreasing the risk of diseases including chronic diseases and other conditions and by interpreting the current data on intakes in the United States and Canada. Oral Antioxidant Nutrients In light of new research on the importance of these vitamins to overall health the Institute of Medicine IOM in Washington . recently released new dietary guidelines for intake of the antioxidant nutrients vitamin C vitamin E carotenoids and selenium. In addition a variety of other nutrients are believed to be involved in antioxidant processes. According to the IOM a dietary antioxidant is defined as a substance in foods that significantly decreases the adverse effects of .
