Khối u trong khu vực Maxillofacial được đặt trong các mô mềm và cứng. Những người nằm trong bộ xương trên khuôn mặt là rất hiếm và có thể có nguồn gốc răng (odontogenic) hoặc phát sinh từ các mô xương (osteogenic). Không có vấn đề dù là lành tính hoặc ác tính, lâm sàng thường có triệu chứng trong một thời gian dài. | 7 Review of Benign Tumors of the Maxillofacial Region and Considerations for Bone Invasion Joachim Prein Tumors in the maxillofacial region are located in the soft and hard tissues. Those located in the facial skeleton are rare and can be of dental origin odontogenic or arise from bony tissues osteogenic . No matter whether they are benign or malignant clinically they often are symptomless for a long time. Only rarely do they cause pain. Even on x-ray films their appearance is very uniform. Most of them present as mono- or polycystic lesions. Even the distinction of whether these lesions are well delineated or not does not help to determine whether a tumor is benign or Although examinations with computed tomography CT or magnetic resonance imaging MRI give much more precise information about the contents and delineation of these lesions in most of the cases it is not possible to establish a diagnosis. This can only be done through a biopsy and a histologic examination. These biopsies should always be open biopsies to receive sufficient material in quantity and quality. This is important because many benign or malignant tumors can present with histologically similar pictures. This is true for odontogenic tumors . for the ameloblastoma and its variants such as ameloblastic fibroma or ameloblastic fibroodontoma . Also it may be difficult to differentiate between fibrous dysplasia and ossifying fibroma osteoblastoma and osteosarcoma or desmoplastic fibroma and fibrosarcoma. A very close cooperation between the clinician pathologist and radiologist is mandatory to receive an exact diagnosis. The pathologist needs all clinical and radiologic information because tumors that are histologically similar may have different diagnoses according to their different anatomic locations. A correct treatment plan can of course only be established with a precise preoperative diagnosis. Odontogenic Tumors and Tumorlike Lesions Tumors and tumorlike lesions of dental .