Tuyển tập báo cáo các nghiên cứu khoa học quốc tế ngành y học dành cho các bạn tham khảo đề tài:Leser-Trélat sign presenting in a patient with ovarian cancer: a case report | JOURNAL OF MEDICAL Sr CASE REPORTS Open Access Case report Leser-Trélat sign presenting in a patient with ovarian cancer a case report Edwin Bolke1 Peter Arne Gerber2 Matthias Peiper3 Wolfram Trudo Knoefel3 Mathias Cohnen4 Christiane Matuschek1 Wilfried Budach1 Rainer Engers5 and Stephan Gripp1 Addresses Department of Radiation Therapy and Radiation Oncology University of Dusseldorf Moorenstrasse 5 40225 Dusseldorf Germany 2Department of Dermatology University of Dusseldorf Moorenstrasse 5 40225 Dusseldorf Germany 3Department of Surgery University of Dusseldorf Moorenstrasse 5 40225 Dusseldorf Germany 4Institute of Diagnostic Radiology University of Dusseldorf Moorenstrasse 5 40225 Dusseldorf Germany 5Department of Pathology University of Dusseldorf Moorenstrasse 5 40225 Dusseldorf Germany Email EB - boelke@ PAG - MP - Peiper@ WTK - knoefel@ MC - cohnen@ CM - matuschek@ WB - RE - engers@ SG - gripp@ Corresponding author Received 28 February 2008 Accepted 9 February 2009 Published 23 July 2009 Journal of Medical Case Reports 2009 3 8583 doi 1752-1947-3-8583 This article is available from http casesjournal article view 8583 2009 Bolke et al. licensee Cases Network Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License http licenses by which permits unrestricted use distribution and reproduction in any medium provided the original work is properly cited. Abstract Introduction Seborrheic keratoses are very common findings in elderly patients. However a sudden onset and dramatic increase in the number and size of these benign lesions deserves special attention since this may represent the Leser Trélat sign a rare paraneoplastic cutaneous syndrome. .