Tuyển tập báo cáo các nghiên cứu khoa học quốc tế ngành y học dành cho các bạn tham khảo đề tài: Distress related to myocardial infarction and cardiovascular outcome: a retrospective observational study | von Kănel et al. BMC Psychiatry 2011 11 98 http 1471-244X 11 98 BMC Psychiatry RESEARCH ARTICLE Open Access Distress related to myocardial infarction and cardiovascular outcome a retrospective observational study 1 2 2 1 Roland von Kanel 1 Roman Hari Jean-Paul Schmid Hugo Saner and Stefan Begré Abstract Background During acute coronary syndromes patients perceive intense distress. We hypothesized that retrospective ratings of patients MI-related fear of dying helplessness or pain all assessed within the first year post-MI are associated with poor cardiovascular outcome. Methods We studied 304 patients 61 11 years 85 men who after a median of 52 days range 12-365 days after index MI retrospectively rated the level of distress in the form of fear of dying helplessness or pain they had perceived at the time of MI on a numeric scale ranging from 0 no distress to 10 extreme distress . Non-fatal hospital readmissions due to cardiovascular disease CVD related events . recurrent MI elective and non-elective stent implantation bypass surgery pacemaker implantation cerebrovascular incidents were assessed at follow-up. The relative CVD event risk was computed for a clinically meaningful 2-point increase of distress using Cox proportional hazard models. Results During a median follow-up of 32 months range 16-45 45 patients experienced a CVD-related event requiring hospital readmission. Greater fear of dying HR 95 CI helplessness HR 95 CI or pain HR 95 CI were significantly associated with an increased CVD risk without adjustment for covariates. A similarly increased relative risk emerged in patients with an unscheduled CVD-related hospital readmission . when excluding patients with elective stenting fear of dying HR 95 CI helplessness 95 CI pain HR 95 CI . In the fully-adjusted models controlling for age the number of diseased coronary vessels .
