Tuyển tập báo cáo các nghiên cứu khoa học quốc tế ngành y học dành cho các bạn tham khảo đề tài: Long term life dissatisfaction and subsequent major depressive disorder and poor mental health | Rissanen et al. BMC Psychiatry 2011 11 140 http 1471-244X 11 140 BMC Psychiatry RESEARCH ARTICLE Open Access Long term life dissatisfaction and subsequent major depressive disorder and poor mental health 125 1 15 1 Teemu Rissanen Heimo Viinamaki Kirsi Honkalampi Soili M Lehto Jukka Hintikka Tarja Saharinen and Heli Koivumaa-Honkanen1 3 4 Abstract Background Poor mental health especially due to depression is one of the main public health problems. Early indicators of poor mental health in general population are needed. This study examined the relationship between long-term life dissatisfaction and subsequent mental health including major depressive disorder. Method Health questionnaires were sent to a randomly selected population-based sample in 1998 and repeated in 1999 and 2001. In 2005 a clinically studied sub-sample n 330 was composed of subjects with n 161 or without n 169 repeatedly reported adverse mental symptoms at all three previous data collection times. Clinical symptom assessments were performed with several psychometric scales life satisfaction LS depression HDRS BDI hopelessness HS mental distress GHQ dissociative experiences DES and alexithymia TAS . The longterm life dissatisfaction burden was calculated by summing these life satisfaction scores in 1998 1999 2001 and dividing the sum into tertiles. Psychiatric diagnoses were confirmed by SCID-I for DSM-IV in 2005. Logistic regression analyses were performed to assess the studied relationship. Results The previous life dissatisfaction burden associated with adverse socio-demographic life style and clinical factors. In adjusted logistic regression analyses it was independently and strongly associated with subsequent major depressive disorder in 2005 even when the concurrent LS score in 2005 was included in the model. Excluding those with reported major depressive disorder in 1999 did not alter this finding. Limitations MDD in 1999 was based on self-reports and not on .
