Tuyển tập báo cáo các nghiên cứu khoa học quốc tế ngành y học dành cho các bạn tham khảo đề tài: REFLEX, a social-cognitive group treatment to improve insight in schizophrenia: study protocol of a multi-center RCT | Pijnenborg et al. BMC Psychiatry 2011 11 161 http 1471-244X 11 161 BMC Psychiatry STUDY PROTOCOL Open Access REFLEX a social-cognitive group treatment to improve insight in schizophrenia study protocol of a multi-center RCT GHM Pijnenborg1 2 4 Mark Van der Gaag5 6 Claudi LH Bockting2 Lisette Van der Meer3 4 and André Aleman2 4 Abstract Background Insight is impaired in a majority of people with schizophrenia. Impaired insight is associated with poorer outcomes of the disorder. Based on existing literature we developed a model that explains which processes may possibly play a role in impaired insight. This model was the starting point of the development of REFLEX a brief psychosocial intervention to improve insight in schizophrenia. REFLEX is a 12-sessions group training consisting of three modules of four sessions each. Modules in this intervention are coping with stigma you and your personal narrative and you in the present . Methods Design REFLEX is currently evaluated in a multicenter randomized controlled trial. Eight mental health institutions in the Netherlands participate in this evaluation. Patients are randomly assigned to either REFLEX or an active control condition existing of cognitive remediation exercises in a group. In a subgroup of patients fMRI scans are made before and after training in order to assess potential haemodynamic changes associated with the effects of the training. Discussion REFLEX is one of the few interventions aiming specifically to improving insight in schizophrenia and has potential value for improving insight. Targeting insight in schizophrenia is a complex task that comes with several methodological issues. These issues are addressed in the discussion of this paper. Trial registration Current Controlled Trials ISRCTN50247539 Keywords schizophrenia insight treatment self-reflection self-stigma perspective-taking 1. Background The percentage of persons with schizophrenia who have only limited insight into .
