Tuyển tập báo cáo các nghiên cứu khoa học quốc tế ngành y học dành cho các bạn tham khảo đề tài: Excessive substance use in bipolar disorder is associated with impaired functioning rather than clinical characteristics, a descriptive study | Lagerberg et al. BMC Psychiatry 2010 10 9 http 1471-244X 10 9 BMC Psychiatry RESEARCH ARTICLE Open Access Excessive substance use in bipolar disorder is associated with impaired functioning rather than clinical characteristics a descriptive study Trinci I 4 1 arharn 1 lo A Andrci2CCQH1 3 DiCittiCir A Dimnori3 A l isiH o Rarn3 Ctjkti I urcmn3 InririH An ri 73 4 nine V Ldyeibeiy Ole A Andiedssen Pettei A Rinyen Akidn O Deiy Sdid Ldisson inyiid Ayditz Kjetil Sundet2 Inyiid Melle1 3 Abstract Background There is d stiony dssocidtion between bipoldi disoidei BD dnd substdnce use disoidei SUD . The clinicdl dnd functiondl coiieldtes of SUD in BD die still uncled dnd little is known dbout the iole of excessive substdnce use thdt does not meet SUD ciiteiid. Thus the dims of the cuiient study were to investiydte lifetime idtes of illicit substdnce use in BD ieldtive to the noimdl populdtion dnd if there die differences in clinicdl dnd functiondl fedtuies between BD pdtients with dnd without excessive substdnce use. Methods 125 consecutively ieciuited BD in- dnd outpdtients from the Oslo Univeisity Hospitdls dnd 327 peisons idndomly didwn fiom the populdtion in Oslo NoiWdy pditicipdted. Clinicdl dnd functiondl vdiidbles were dssessed. Excessive substdnce use wds defined ds DSM-IV SUD dnd oi excessive use dccoidiny to predefined ciiteiid. Results The idte of lifetime illicit substdnce use wds siynificdntly hiyhei dmony pdtients compdied to the reference populdtion OR CI p .001 . Pdtients with excessive substdnce use 45 of totdl hdd pooiei educdtiondl level occupdtiondl stdtus GAF-scoies dnd medicdtion complidnce with d tiend towdids hiyhei suiciddlity idtes compdied to pdtients without. Theie weie no siynificdnt yioup diffeiences in cuiient symptom levels oi disedse couise between yioups. Conclusion The peicentdye of pdtients with BD thdt hdd tiied illicit substdnces wds siynificdntly hiyhei thdn in the noimdl populdtion. BD pdtients with .