Tuyển tập báo cáo các nghiên cứu khoa học quốc tế ngành y học dành cho các bạn tham khảo đề tài: Depression and loneliness in Jamaicans with sickle cell disease | Asnani et al. BMC Psychiatry 2010 10 40 http 1471-244X 10 40 BMC Psychiatry RESEARCH ARTICLE Open Access Depression and loneliness in Jamaicans with sickle cell disease Monika R Asnani Raphael Fraser Norma A Lewis Marvin E Reid Abstract Background Sickle cell disease SCD is the commonest genetic disorder in Jamaica and has life-long implications for those afflicted with it. It is well known that depression and loneliness may exist in those with chronic diseases but the coexistence of depression and loneliness in people with sickle cell disease is not clear. The aim of this study is to determine the prevalence of and factors associated with depression and loneliness in the Jamaica Sickle Cell Cohort Study and its age and sex matched controls. Methods 277 patients with SCD and 65 controls were administered a questionnaire that studied demographics disease severity depression and loneliness. Regression analyses were done to examine relationships between outcomes and associated variables. Results Depression was found in of patients and in controls. Loneliness scores were also significantly higher in patients than in controls . Depression was significantly associated with unemployment OR p-value whereas unemployment p-value and lower educational attainment were significantly associated with loneliness. In patients with SCD depression was significantly associated with being unemployed OR 95 CI p-value presence of a leg ulcer OR 95 CI p-value frequent visits OR 95 CI p-value and frequent painful crises OR 95 CI p-value . Not being employed Coef. p-value and higher educational attainment tertiary vs. primary education Coef. p-value were significant associations with loneliness after adjusting for genotype. Conclusions Health workers need to actively look for and manage these problems to optimize their patients total
