Tuyển tập báo cáo các nghiên cứu khoa học quốc tế ngành y học dành cho các bạn tham khảo đề tài: The course of untreated anxiety and depression, and determinants of poor one-year outcome: a one-year cohort study | van Beljouw et al. BMC Psychiatry 2010 10 86 http 1471-244X 10 86 BMC Psychiatry RESEARCH ARTICLE Open Access The course of untreated anxiety and depression and determinants of poor one-year outcome a one-year cohort study lied l l I an Rdllr ii HA 1 Pũtor R Wi h ì . L 1-lii r c I lỉỉrvcirc2 IW ITI A I van l lanA lll 3 P onrl i A II I Amiriii 4 - Ilse MJ van Beljouw Peter FM veniaak rim Cuijpers Harm WJ van Marwijk Brenda Wjn Peiuinix Abstract Background Little is known about the course and outcome of untreated anxiety and depression in patients with and without a self-perceived need for care. The aim of the present study was to examine the one-year course of untreated anxiety and depression and to determine predictors of a poor outcome. Method Baseline and one-year follow-up data were used of 594 primary care patients with current anxiety or depressive disorders at baseline established by the Composite Interview Diagnostic Instrument CIDI from the Netherlands Study of Depression and Anxiety NESDA . Receipt of and need for care were assessed by the Perceived Need for Care Questionnaire PNCQ . Results In depression treated and untreated patients with a perceived treatment need showed more rapid symptom decline but greater symptom severity at follow-up than untreated patients without a self-perceived mental problem or treatment need. A lower education level lower income unemployment loneliness less social support perceived need for care number of somatic disorders a comorbid anxiety and depressive disorder and symptom severity at baseline predicted a poorer outcome in both anxiety and depression. When all variables were considered at the same time only baseline symptom severity appeared to predict a poorer outcome in anxiety. In depression a poorer outcome was also predicted by more loneliness and a comorbid anxiety and depressive disorder. Conclusion In clinical practice special attention should be paid to exploring the need for care among .