Tuyển tập báo cáo các nghiên cứu khoa học quốc tế ngành y học dành cho các bạn tham khảo đề tài: Multifamily Group Psychoeducation and Cognitive Remediation for First-Episode Psychosis: A Randomized Controlled Trial | Breitborde et al. BMC Psychiatry 2011 11 9 http 1471-244X 11 9 BMC Psychiatry STUDY PROTOCOL Open Access Multifamily Group Psychoeducation and Cognitive Remediation for First-Episode Psychosis A Randomized Controlled Trial 3 1 Nicholas JK Breitborde Francisco A Moreno Natalie Mai-Dixon Rachele Peterson Linda Durst Beth Bernstein1 2 Seenaiah Byreddy1 William R McFarlane4 Abstract Background Multifamily group psychoeducation MFG has been shown to reduce relapse rates among individuals with first-episode psychosis. However given the cognitive demands associated with participating in this intervention . learning and applying a structured problem-solving activity the cognitive deficits that accompany psychotic disorders may limit the ability of certain individuals to benefit from this intervention. Thus the goal of this study is to examine whether individuals with first-episode psychosis who participate simultaneously in MFG and cognitive remediation-an intervention shown to improve cognitive functioning among individuals with psychotic disorders-will be less likely to experience a relapse than individuals who participate in MFG alone. Methods Design Forty individuals with first-episode psychosis and their caregiving relative will be recruited to participate in this study. Individuals with first-episode psychosis will be randomized to one of two conditions i MFG with concurrent participation in cognitive remediation or ii MFG alone. The primary outcome for this study is relapse of psychotic symptoms. We will also examine secondary outcomes among both individuals with first-episode psychosis . social and vocational functioning health-related quality of life service utilization independent living status and cognitive functioning and their caregiving relatives . caregiver burden anxiety and depression Discussion Cognitive remediation offers the possibility of ameliorating a specific deficit . deficits in cognitive functioning .