Tuyển tập báo cáo các nghiên cứu khoa học quốc tế ngành y học dành cho các bạn tham khảo đề tài: Disrupting the rhythm of depression using Mobile Cognitive Therapy for recurrent depression: randomized controlled trial design and protocol | Bockting et al. BMC Psychiatry 2011 11 12 http 1471-244X 11 12 BMC Psychiatry STUDY PROTOCOL Open Access Disrupting the rhythm of depression using Mobile Cognitive Therapy for recurrent depression randomized controlled trial design and protocol In I loll I I I Rml tiim Lommii n l mlz1 I illinn ũ l urnn2 Rilim Crnlt2 3 Rimlirnn 1 aia t aldm4 Rmlnnrt Ị5 Claudi Ln Bockting Gemma D KUk Lillian van der Kamp Filip Dilin Evelien van valen Robert Dcnueveis I_I n imm l lnriA uL6 DI r 1 I u t-AZA 7 I_I -A I ZA ZA m DI ZAZA V3 I -A r lz I Ì ZA IzIzza z7 8 A -A ZZA I o ZA r lz9 Harm van Marwijk rim Cuijpers neieen Riper Jack Dekker Aaron I Deck Abstract Background Major depressive disorder MDD is projected lu rank secund un a list uf 15 major diseases in terms uf burden in 2030. The major contribution of MDD lo disability and health care costs is largely due lo its highly recurrent nature. Accordingly efforts to reduce the disabling effects of this chronic condition should shift to preventing recurrence especially in patients at high risk of recurrence. Given its high prevalence and the fact that interventions are necessary during the remitted phase new approaches are needed to prevent relapse in depression. Methods design The best established effective and available psychological intervention is cognitive therapy. However it is costly and not available for most patients. Therefore we will compare the effectiveness and costeffectiveness of self-management supported by online CT accompanied by SMS based tele-monitoring of depressive symptomatology . Mobile Cognitive Therapy M-CT versus treatment as us usual TAU . Remitted patients n 268 with at least two previous depressive episodes will be recruited and randomized over 1 M-CT in addition to TAU versus 2 TAU alone with follow-ups at 3 12 and 24 months. Randomization will be stratified for number of previous episodes and type of treatment as usual. Primary outcome is time until relapse recurrence .
