Tuyển tập báo cáo các nghiên cứu khoa học quốc tế ngành y học dành cho các bạn tham khảo đề tài: Low-intensity blue-enriched white light (750 lux) and standard bright light (10 000 lux) are equally effective in treating SAD. A randomized controlled study | Meesters et al. BMC Psychiatry 2011 11 17 http 1471-244X 11 17 BMC Psychiatry RESEARCH ARTICLE Open Access Low-intensity blue-enriched white light 750 lux and standard bright light 10 000 lux are equally effective in treating SAD. A randomized controlled study 1 1 23 4 Ybe Meesters Vera Dekker Luc JM Schlangen Elske H Bos Martine J Ruiter Abstract Background Photoreceptor cells containing melanopsin play a role in the phase-shifting effects of short-wavelength light. In a previous study we compared the standard light treatment SLT of SAD with treatment using shortwavelength blue-enriched white light BLT . Both treatments used the same illuminance 10 000 lux and were equally highly effective. It is still possible however that neither the newly-discovered photoreceptor cells nor the biological clock play a major role in the therapeutic effects of light on SAD. Alternatively these effects may at least be partly mediated by these receptor cells which may have become saturated as a result of the high illuminances used in the therapy. This randomized controlled study compares the effects of low-intensity BLT to those of high-intensity SLT. Method In a 22-day design 22 patients suffering from a major depression with a seasonal pattern SAD were given light treatment 10 000 lux for two weeks on workdays. Subjects were randomly assigned to either of the two conditions with gender and age evenly distributed over the groups. Light treatment either consisted of 30 minutes SLT 5000 K with the EnergyLight Philips Consumer Lifestyle with a vertical illuminance of 10 000 lux at eye position or BLT 17 000 K with a vertical illuminance of 750 lux using a prototype of the EnergyLight which emitted a higher proportion of short-wavelengths. All participants completed questionnaires concerning mood activation and sleep quality on a daily basis. Mood and energy levels were also assessed on a weekly basis by means of the SIGH-SAD and other assessment tools. Results On
