Báo cáo y học: " Predictors and correlates for weight changes in patients co-treated with olanzapine and weight mitigating agents; a post-hoc analysis"

Tuyển tập báo cáo các nghiên cứu khoa học quốc tế ngành y học dành cho các bạn tham khảo đề tài: Predictors and correlates for weight changes in patients co-treated with olanzapine and weight mitigating agents; a post-hoc analysis | BioMed Central BMC Psychiatry Open Access Research article Predictors and correlates for weight changes in patients co-treated with olanzapine and weight mitigating agents a post-hoc analysis Virginia L Stauffer 1 Ilya Lipkovich2 Vicki Poole Hoffmann3 Alexandra N Heinloth4 H Scott McGregor1 and Bruce J Kinon3 Address Neuroscience Lilly USA LLC Indianapolis IN 46285 USA Statistics Eli Lilly and Company IN 46285 USA 3Neuroscience Eli Lilly and Company IN 46285 USA and 4i3Statprobe subsidiary of United Health Group Ann Arbor MI USA Email Virginia L Stauffer - Stauffer_Virginia@ Ilya Lipkovich - Lipkovich_Ilya_A@ Vicki Poole Hoffmann - Hoffmann_Vicki_Poole@ Alexandra N Heinloth - H Scott McGregor - Mcgregor_Scott_H@ Bruce J Kinon - Kinon_Bruce@ Corresponding author Published 28 March 2009 Received 20 August 2008 BMC Psychiatry 2009 9 12 doi 1471-244X-9-12 Accepted 28 March 2009 This article is available from http 1471-244X 9 12 2009 Stauffer et al licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License http licenses by which permits unrestricted use distribution and reproduction in any medium provided the original work is properly cited. Abstract Background This study focuses on exploring the relationship between changes in appetite or eating behaviors and subsequent weight change for adult patients with schizophrenia or bipolar disorder treated with olanzapine and adjunctive potential weight mitigating pharmacotherapy. The aim is not to compare different weight mitigating agents but to evaluate patients characteristics and changes in their eating behaviors during treatment. Identification of patient subgroups with different degrees of susceptibility to the effect of weight mitigating agents during olanzapine treatment may aid clinicians in treatment decisions. .

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