Báo cáo y học: "The self-reported Montgomery-Åsberg depression rating scale is a useful evaluative tool in major depressive disorder"

Tuyển tập báo cáo các nghiên cứu khoa học quốc tế ngành y học dành cho các bạn tham khảo đề tài: The self-reported Montgomery-Åsberg depression rating scale is a useful evaluative tool in major depressive disorder | BMC Psychiatry BioMed Central Open Access The self-reported Montgomery-Asberg depression rating scale is a useful evaluative tool in major depressive disorder Bruno Fantino 1 and Nicholas Moore 2 Address 1ADIM-AGORAS 112 cours Albert Thomas 69008 LYON France and 2Département de Pharmacologie CHU de Bordeaux - Université Victor Segalen Case 36 33076 Bordeaux France Email Bruno Fantino - Nicholas Moore - Corresponding authors Published 27 May 2009 Received 29 April 2008 BMC Psychiatry 2009 9 26 doi 1471-244X-9-26 Accepted 27 May 2009 This article is available from http 1471-244X 9 26 2009 Fantino and Moore licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License http licenses by which permits unrestricted use distribution and reproduction in any medium provided the original work is properly cited. Abstract Background The use of Patient-reported Outcomes PROs as secondary endpoints in the development of new antidepressants has grown in recent years. The objective of this study was to assess the psychometric properties of the 9-item patient-administered version of the Montgomery-Asberg Depression Rating Scale MADRS-S . Methods Data from a multicentre double-blind 8-week randomised controlled trial of 278 outpatients diagnosed with Major Depressive Disorder were used to evaluate the validity reliability and sensitivity to change of the MADRS-S using psychometric methods. A Receiver Operating Characteristic ROC curve was plotted to identify the most appropriate threshold to define perceived remission. Results No missing values were found at the item level indicating good acceptability of the scale. The construct validity was satisfactory all items contributed to a common underlying concept as expected. The correlation between MADRS-S and physicians MADRS was moderate r p

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