Hình 9-11. a) xem trước phẫu thuật của một phụ nữ 58 tuổi người gần đây đã bị mất 110 pounds. b) 1 bệnh nhân năm sau khi một sự đổi mới, cắt bỏ trực tiếp thứ hai của những nếp gấp nasolabial, và tái tạo bề mặt laser CO2 của những vết sẹo. (In lại từ phẫu thuật thẩm mỹ 2 / e | 96 Tissue Surgery p vs. CG Figure 8-2. Clamping the femoral artery is as effective at preconditioning the flap as a noninvasive tourniquet applied to the rat hind limb followed by 30 minutes limb Average flap necrosis was in the control group CG 11 in the preclamping group PG in the femoral ischemic group FG and 24 in the tourniquet group TG . All preconditioned animals had a significantly smaller area of flap necrosis than did the control animals p vs. CG . The differences between PG FG and TG groups were not significant. the femoral artery and vein. Short-term limb ischemia has a preconditioning effect on 47 Thus longer-term limb ischemia might also influence flap ischemia reperfusion injury. Recently Addison et confirmed our data on the effectiveness of noninvasive acute remote IP for global protection of skeletal muscle against ischemic necrosis in a large animal model. Three 10-minute cycles of occlusion and reperfusion in a pig hind limb using a tourniquet significantly reduced infarctions of the latissimus dorsi gracilis and rectus abdominis muscles by 55 60 and 55 respectively compared to a control group. Whether remote ischemic preconditioning could be induced by a late mechanism was also A rat hind limb was subjected to 10 minutes of ischemia and 30 minutes of reperfusion with a tourniquet 24 hours before flap ischemia. This protocol increased red blood cell velocity in the capillaries and first-order arterioles and venules and increased capillary flow as well as decreased leukocyte sticking in a cremaster model and thus attenuated early ischemia-reperfusion injury in muscle flaps. On the other hand it did not improve flap survival in adipocutaneous flaps. These findings indicate p vs. CG Figure 8-3. Both classic and remote acute ischemic preconditioning improve microcirculation of muscle flaps after ischemia in a rat Capillary flow results capillary flow
