Tuyển tập báo cáo các nghiên cứu khoa học quốc tế ngành y học dành cho các bạn tham khảo đề tài: Delivery of a baby with severe combined immunodeficiency at 31 weeks gestation following an extreme preterm prelabour spontaneous rupture of the membranes: a case report | Journal of Medical Case Reports BioMed Central Open Access Case report Delivery of a baby with severe combined immunodeficiency at 31 weeks gestation following an extreme preterm prelabour spontaneous rupture of the membranes a case report Sally J Watkinson Christopher CT Lee and Christopher V Steer Address Department of Obstetrics and Gynaecology Princess Royal University Hospital Farnborough Kent UK Email Sally J Watkinson - Christopher CT Lee - Christopher V Corresponding author Published 12 November 2009 Received 28 October 2008 Journal of Medical Case Reports 2009 3 118 doi 1752-1947-3-118 Accepted 12 November 2009 This article is available from http content 3 1 1 18 2009 Watkinson et al licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License http licenses by which permits unrestricted use distribution and reproduction in any medium provided the original work is properly cited. Abstract_ Introduction If left untreated severe combined immunodeficiency can lead to an acute susceptibility to infection. The intrauterine environment is sterile until the amniotic membranes rupture. The vaginal flora then ascends into the genital tract thus increasing the risk of chorioamnionitis. An extremely premature and prolonged membrane rupture is associated with a dismal prognosis for an immunocompetent preterm fetus. There are no case reports to date that detail the outcome of an immunocompromised preterm baby following prolonged rupture of membranes. Case presentation We present the case of a 32-year-old Indian woman who delivered a 31week gestational baby who had a severe combined immunodeficiency following premature prelabour prolonged rupture of the membranes at the 14th week of .
