Tuyển tập báo cáo các nghiên cứu khoa học quốc tế ngành y học dành cho các bạn tham khảo đề tài: Health, human rights, and the conduct of clinical research within oppressed populations | Globalization and Health BioMed Central Debate Open Access Health human rights and the conduct of clinical research within oppressed populations Edward J Mills 1 2 and Sonal Singh2 3 4 Address Programme in International Human Rights Law University of Oxford Oxford UK 2Department of Pharmacy Rhodes University Grahamstown Eastern Cape South Africa 3Bloomberg School of Public Health Johns Hopkins University Baltimore USA and 4School of Medicine Wake Forest University Winston-Salem USA Email Edward J Mills - emills@ Sonal Singh - sosingh@ Corresponding author Published 8 November 2007 Received 23 April 2007 Accepted 8 November 2007 Globalization and Health 2007 3 10 doi l 744-8603-3-10 This article is available from http content 3 1 10 2007 Mills and Singh licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License http licenses by which permits unrestricted use distribution and reproduction in any medium provided the original work is properly cited. Abstract Background Clinical trials evaluating interventions for infectious diseases require enrolling participants that are vulnerable to infection. As clinical trials are conducted in increasingly vulnerable populations issues of protection of these populations become challenging. In settings where populations are forseeably oppressed the conduct of research requires considerations that go beyond common ethical concerns and into issues of international human rights law. Discussion Using examples of HIV prevention trials in Thailand hepatitis-E prevention trials in Nepal and malaria therapeutic trials in Burma Myanmar we address the inadequacies of current ethical guidelines when conducting research within oppressed populations. We review existing legislature in the United States and United Kingdom that may be used against foreign investigators if trial hardships exist.
