Tuyển tập báo cáo các nghiên cứu khoa học quốc tế ngành y học dành cho các bạn tham khảo đề tài: Tampering by office-based methadone maintenance patients with methadone take home privileges: a pilot study | Harm Reduction Journal BioMed Central Case Report Open Access Tampering by office-based methadone maintenance patients with methadone take home privileges a pilot study Michael Varenbut David Teplin Jeff Daiter Barak Raz Andrew Worster Pasha Emadi-Konjin Nathan Frank Alan Konyer Iris Greenwald and Melissa Snider-Adler Address Ontario Addiction Treatment Centres Canada Email Michael Varenbut - mvarenbut@ David Teplin - dteplin@ Jeff Daiter - jdaiter@ Barak Raz - braz@ Andrew Worster - aworster@ Pasha Emadi-Konjin - info@ Nathan Frank - nfrank@ Alan Konyer - akonyer@ Iris Greenwald - igreenwald@ Melissa Snider-Adler - msnider-adler@ Corresponding author Published 30 October 2007 Received 30 April 2007 Accepted 30 October 2007 Harm Reduction Journal 2007 4 15 doi l 477-7517-4-15 This article is available from http content 4 1 15 2007 Teplin et al licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License http licenses by which permits unrestricted use distribution and reproduction in any medium provided the original work is properly cited. Abstract Methadone Maintenance Treatment MMT is among the most widely studied treatments for opiate dependence with proven benefits for patients and society. When misused however methadone can also be lethal. The issue of methadone diversion is a major concern for all MMT programs. A potential source for such diversion is from those MMT patients who receive daily take home methadone doses. Using a reverse phase high performance liquid chromatography method seven of the nine patients who were randomly selected to have all of their remaining methadone take home doses within a 24 hour period analyzed returned lower than expected quantities of methadone. This finding suggests the possibility that such patients may have
