Đau cơ bắp sau khi tập thể dục bất thường được cho là kết quả từ hoạt động lặp đi lặp lại kéo dài của cơ xương. "Bài tập lập dị" khởi đầu một chuỗi các sự kiện bao gồm cytoskeletal giáng hóa cơ, viêm, và tu sửa như vậy mà sau buổi tập thể dục dẫn đến chấn thương và đau nhức. | Morphologic and Mechanical Basis of Delayed-Onset Muscle Soreness Richard L. Lieber PhD and Jan Fridén MD PhD Abstract Muscle pain after unaccustomed exercise is believed to result from repetitive active lengthening of skeletal muscle. This eccentric exercise initiates a sequence of events that includes muscle cytoskeletal breakdown inflammation and remodeling such that subsequent exercise sessions result in less injury and soreness. Recent studies of eccentric exercise using well-defined animal models have identified the mechanical and cellular events associated with the injury-repair process. In addition neurophysiologic studies have elucidated mechanisms of pain that operate in skeletal muscle. Taken together these studies improve our understanding of the muscle injury process and will lead to rational therapeutic interventions to facilitate recovery. J Am Acad Orthop Surg 2002 10 67-73 Delayed-onset muscle soreness DOMS or what is commonly described as postexercise muscle soreness is the sensation of muscular discomfort and pain during active contractions that occurs in a delayed fashion after strenuous exercise. Usually the initial symptoms are most evident at the muscle tendon junction and thereafter spread throughout the entire muscle. Skeletal muscle soreness and injury are associated with intense exercise. The soreness and accompanying muscle damage are even more pronounced if the exercise performed is new to the individual. Thus even individuals who are in excellent athletic condition may experience muscle soreness and damage when performing exercise to which they are unaccustomed. The relationship between the development of DOMS and the loss of muscle strength has yet to be explicitly proven. Symptoms Sore muscles after exercise are usually described as stiff tender or aching. The stiffness associated with DOMS is not a function of antagonistic muscular action but is probably caused by edema occurring in the perimuscular connective The symptoms
