Tuyển tập báo cáo các nghiên cứu khoa học quốc tế ngành y học dành cho các bạn tham khảo đề tài: Water intoxication presenting as maternal and neonatal seizures: a case report | Journal of Medical Case Reports BioMed Central Open Access Case report Water intoxication presenting as maternal and neonatal seizures a case report Timothy H Chapman and Mark Hamilton Address Department of Intensive Care St Georges Hospital London SW17 0QT UK Email Timothy H Chapman - Mark Hamilton - markhamilton@ Corresponding author Published 4 December 2008 Received 28 February 2008 Journal of Medical Case Reports 2008 2 366 doi 1752-1947-2-366 Accepted 4 December 2008 This article is available from http content 2 1 366 2008 Chapman and Hamilton licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License http licenses by which permits unrestricted use distribution and reproduction in any medium provided the original work is properly cited. Abstract Introduction We present an unusual case of fitting in the mother and newborn child and the challenges faced in the management of their hyponatraemia due to water intoxication. Case presentation A previously well 37-year-old primigravid Caucasian woman presented with features mimicking eclampsia during labour. These included confusion reduced consciousness and seizures but without a significant history of hypertension proteinuria or other features of preeclampsia. Her serum sodium was noted to be low at III mmol litre as was that of her newborn baby. She needed anti-convulsants with subsequent intubation to stop the fitting and was commenced on a hypertonic saline infusion with frequent monitoring of serum sodium. There is a risk of long-term neurological damage from central pontine myelinolysis if the hyponatraemia is corrected too rapidly. Mother and baby went on to make a full recovery without any long-term neurological complications. Conclusion There is little consensus on the treatment of life-threatening hyponatraemia. Previous articles have .