Báo cáo y học: "Cytomegalovirus-associated splenic infarcts in a female patient with Factor V Leiden mutation: a case report"

Tuyển tập báo cáo các nghiên cứu khoa học quốc tế ngành y học dành cho các bạn tham khảo đề tài: Cytomegalovirus-associated splenic infarcts in a female patient with Factor V Leiden mutation: a case report | Journal of Medical Case Reports BioMed Central Open Access Case report Cytomegalovirus-associated splenic infarcts in a female patient with Factor V Leiden mutation a case report Lihi Atzmony Nili Saar Tamar Chundadze Yaron Arbel Dan Justo and Noa Mashav Address Department of Internal Medicine D Tel-Aviv Sourasky Medical Center 6 Weitzman Street Tel-Aviv 64239 Israel Email Lihi Atzmony - lihi_a@ Nili Saar - Tamar Chundadze - tamar0102@ Yaron Arbel - yaronarbel@ Dan Justo - justo1@ Noa Mashav - Corresponding author Published 16 December 2008 Received 15 March 2008 Journal of Medical Case Reports 2008 2 385 doi l752-l947-2-385 Accepted 16 December 2008 This article is available from http content 2 l 385 2008 Atzmony et al licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License http licenses by which permits unrestricted use distribution and reproduction in any medium provided the original work is properly cited. Abstract Introduction Cytomegalovirus-associated thrombosis has rarely been reported in the medical literature and if so mainly in immunocompromized patients. Case presentation We report the case of a 36-year-old Caucasian woman with acute cytomegalovirus infection presenting with spontaneous splenic infarcts. Trans-esophageal echocardiography did not show any vegetations or mural thrombi. The patient was also found to be heterozygous for the Factor V Leiden mutation. Anticoagulation treatment was considered but ruled out since cytomegalovirus was the obvious trigger for thrombosis in this patient. To the best of our knowledge this is only the third report to date of cytomegalovirus-associated splenic infarcts. Conclusion This case report serves as additional evidence for the role of cytomegalovirus in thrombosis. Introduction Cytomegalovirus .