Tuyển tập báo cáo các nghiên cứu khoa học quốc tế ngành y học dành cho các bạn tham khảo đề tài: Extramammary Paget's disease of the penis: a case report and review of the literature | Journal of Medical Case Reports BioMed Central Open Access Case report Extramammary Paget s disease of the penis a case report and review of the literature Kingsley C Ekwueme1 Hani D Zakhour2 and Nigel J Parr 1 Address Regional Cancer Centre Department of Urology Wirral University Teaching Hospital Arrowe Park Road Upton Wirral CH49 5PE UK and 2Department of Histopathology and Clinical Cytology Wirral University Teaching Hospital Arrowe Park Road Upton Wirral CH49 5PE UK Email Kingsley C Ekwueme - kingsleyekwueme@ Hani D Zakhour - Nigel J Parr - nigelparr@ Corresponding author Published 6 January 2009 Received 5 February 2008 Journal of Medical Case Reports 2009 3 4 doi 1752-1947-3-4 Accepted 6 January 2009 This article is available from http content 3 1 4 2009 Ekwueme et al licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License http licenses by which permits unrestricted use distribution and reproduction in any medium provided the original work is properly cited. Abstract Introduction Extramammary Paget s disease is a rare cutaneous slow growing intraepithelial adenocarcinoma developing in the apocrine gland-bearing areas. Isolated Paget s disease of the penis is extremely rare. Case presentation We describe the case of an 87-year-old Caucasian male who presented with a non-healing erythematous plaque on the shaft of the penis previously misdiagnosed as Bowen s disease. The diagnosis was made histologically on the excised specimen and was supported by immunohistochemical staining. Conclusion Extramammary Paget s disease is a rare disease which can mimic various types of dermatosis. A high index of suspicion is required combined with biopsy and immunohistochemical staining in order to make the correct diagnosis. Long-term follow-up is mandatory in these patients in order to .
