Tuyển tập báo cáo các nghiên cứu khoa học quốc tế ngành y học dành cho các bạn tham khảo đề tài: Celiac disease as a potential cause of idiopathic portal hypertension: a case report | Journal of Medical Case Reports BioMed Central Open Access Celiac disease as a potential cause of idiopathic portal hypertension a case report Farhad Zamani1 Afsaneh Amiri 1 Ramin Shakeri2 Ali Zare3 and Mehdi Mohamadnejad1 2 Address Gastrointestinal and Liver Disease Research Center Firouzgar Hospital Iran University of Medical Sciences Tehran Iran 2Digestive Disease Research Center Shariati Hospital Tehran University of Medical Sciences Tehran Iran and 3Department of Pathology Firouzgar Hospital Iran University of Medical Sciences Tehran Iran Email Farhad Zamani - Afsaneh Amiri - Ramin Shakeri - rshakeri@ Ali Zare - azaremehrjardi@ Mehdi Mohamadnejad - Corresponding author Published 16 February 2009 Received 28 April 2008 Journal of Medical Case Reports 2009 3 68 doi 1752-1947-3-68 Accepted 16 February 2009 This article is available from http content 3 1 68 2009 Zamani et al licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License http licenses by which permits unrestricted use distribution and reproduction in any medium provided the original work is properly cited. Abstract Introduction Idiopathic portal hypertension is a disorder of unknown etiology clinically characterized by portal hypertension splenomegaly and anemia secondary to hypersplenism. Case presentation A 54-year-old man was admitted to our hospital for evaluation of malaise weight loss abdominal swelling and lower limb edema. His paraclinical tests revealed pancytopenia large ascites splenomegaly and esophageal varices consistent with portal hypertension. Duodenal biopsy and serologic findings were compatible with celiac disease. His symptoms improved on a gluten-free diet but his clinical course was further complicated with ulcerative jejunoileitis and intestinal T-cell lymphoma.