Tuyển tập báo cáo các nghiên cứu khoa học quốc tế ngành y học dành cho các bạn tham khảo đề tài: A case report: Pavlovian conditioning as a risk factor of heroin 'overdose' death | Harm Reduction Journal BioMed Central Case Report Open Access A case report Pavlovian conditioning as a risk factor of heroin overdose death Jozsef Gerevich 1 2 Erika Bácskai1 Lajos Farkas2 and Zoltán Danics3 Address 1Addiction Research Institute Budapest 2ELTE University Faculty of Orthopedagogics Budapest Hungary and 3National Institute of Psychiatry Budapest Hungary Email Jozsef Gerevich - gerevichj@ Erika Bácskai - erikabacskai@ Lajos Farkas - lajos@ Zoltán Danics - danics@ Corresponding author Published 25 July 2005 Received 04 January 2005 Harm Reduction Journal 2005 2 11 doi 1477-7517-2-11 Accepted 25 July 2005 This article is available from http content 2 1 1 1 2005 Gerevich et al licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License http licenses by which permits unrestricted use distribution and reproduction in any medium provided the original work is properly cited. Abstract Background The authors present a case illustrating a mechanism leading directly to death which is not rare but has received little attention. Case presentation The case was evaluated by autopsy investigation of morphine concentration in the blood and clinical data. The heroin dose causing the overdose death of a young man who had previously been treated a number of times for heroin addiction did not differ from his dose of the previous day taken in the accustomed circumstances. The accustomed dose taken in a strange environment caused fatal complications because the conditioned tolerance failed to operate. The concentration of morphine in the blood did not exceed the level measured during earlier treatment. Conclusion These results are in line with the data in the literature indicating that morphine concentrations measured in cases of drug-related death do not differ substantially from those measured in cases .
