Tuyển tập báo cáo các nghiên cứu khoa học quốc tế ngành y học dành cho các bạn tham khảo đề tài: Goodpasture's syndrome with positive C-ANCA and normal renal function: A case report | Journal of Medical Case Reports BioMed Central Open Access Goodpasture s syndrome with positive C-ANCA and normal renal function A case report Arunachalam Ramaswami 1 Thiraviyam Kandaswamy1 Tholappan Rajendran1 Hla Aung1 Chakko K Jacob1 Haji Shaukat Zinna1 and Pemasiri Upali Telesinge2 Address Department of Nephrology RIPAS Hospital Brunei Darussalam and - Department of Pathology RIPAS Hospital Brunei Darussalam Email Arunachalam Ramaswami - ramsdr@ Thiraviyam Kandaswamy-tknephro@ Tholappan Rajendran - ammukkannu@ Hla Aung - hlaaung@ Chakko K Jacob - ckjacob@ Haji ShaukatZinna-zinnashaukat@ Pemasiri Upali Telesinge - ptelesinge@ Corresponding author Published 30 June 2008 Received 30 November 2007 Journal of Medical Case Reports 2008 2 223 doi 1752-1947-2-223 Accepted 30 June 2008 This article is available from http content 2 1 223 2008 Ramaswami et al licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License http licenses by which permits unrestricted use distribution and reproduction in any medium provided the original work is properly cited. Abstract Introduction Goodpasture s syndrome consists of a triad of pulmonary hemorrhage rapidly progressive glomerulonephritis and anti-glomerular basement membrane anti-GBM antibodies either in circulation or fixed to the kidney. The absence of renal manifestations is uncommon. We present a case of biopsy proven anti-GBM antibody disease with normal renal function mild urinary abnormalities and positive C-antineutrophil cytoplasmic antibody C-ANCA serology. Case presentation A 44-year-old female was treated for repeated episodes of hemoptysis and one episode of respiratory failure requiring ventilatory support. She had minor urinary abnormalities in the form of microscopic hematuria and non-nephrotic proteinuria. She also .