Di căn xương là bệnh Nguyên nhân phổ biến KHCN của tổn thương phá hủy xương ở người lớn, và sự tham gia của xương cánh tay IS thông thường. Liên quan đến những bệnh nhân có tổn thương phá hoại | Metastatic Bone Disease of the Humerus Frank J. Frassica MD and Deborah A. Frassica MD Abstract Metastatic bone disease is the most common cause of destructive bone lesions in adults and involvement of the humerus is common. Patients with destructive lesions involving 50 of the cortex are treated nonsurgically with external beam irradiation. Patients with diaphyseal lesions involving 50 of the cortex or those with pain after irradiation can be treated with intramedullary nailing to achieve rigid xation. Although closed intramedullary nailing is used most often open nailing with methylmethacrylate is appropriate for destructive lesions in which rigid xation cannot be achieved with closed nailing. Plate xation is acceptable when adequate proximal and distal cortical bone is present for screw purchase although proximal humeral lesions usually are treated with prosthetic arthroplasty. Postoperative external beam irradiation can help prevent disease progression and subsequent loss of xation. However when disease progression persists or rigid internal xation is not feasible because of extensive bone destruction wide resection and reconstruction with a custom prosthesis can be done. J Am Acad Orthop Surg 2003 11 282-288 Metastases to bone are the most frequent cause of destructive lesions to the skeleton in adults. The most common primary malignancies that metastasize to bone are breast lung kidney and prostate carcinoma. The typical distribution of metastatic lesions is to the spine ribs pelvis and proximal limb However almost any primary malignancy may metastasize to bone and any bone in the body may be involved. In the upper extremity the most common location is the humerus usually the proximal third or the diaphysis. Lesions in the distal third of the humerus are less common and typically occur in patients with myeloma or lung or renal carcinomas. Diagnosis of metastatic humeral bone lesions and alternatives for treatment vary depending on whether the .