Tuyển tập báo cáo các nghiên cứu khoa học quốc tế ngành y học dành cho các bạn tham khảo đề tài: Esophageal squamous cell carcinoma presenting with extensive skin lesions: a case report | Journal of Medical Case Reports BioMed Central Case report Open Access Esophageal squamous cell carcinoma presenting with extensive skin lesions a case report GB Iwanski 1 A Block1 G Keller1 J Muench1 S Claus2 W Fiedler1 and C Bokemeyer1 Address Department of Internal Medicine Oncology and Hematology University Hospital Hamburg Eppendorf Martinistrasse 20246 Hamburg Germany and 2Department of Internal Medicine Bethesda Hospital Hamburg Germany Email GB Iwanski - A Block - block@ G Keller - keller@ J Muench - muench@ S Claus - claus@ W Fiedler - fiedler@ C Bokemeyer - Corresponding author Published 21 April 2008 Received 26 September 2007 Journal of Medical Case Reports 2008 2 115 doi 1752-1947-2-115 Accepted 21 April 2008 This article is available from http content 2 1 1 15 2008 Iwanski et al licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License http licenses by which permits unrestricted use distribution and reproduction in any medium provided the original work is properly cited. Abstract Introduction Esophageal squamous cell carcinoma ESCC is the most common histological subtype of cancer in the upper and middle esophagus and is characterized by a high rate of mortality. The incidence of esophageal cancer varies greatly among regions of the world and occurs at a high frequency in Asia and South America. Case presentation In our department a 51-year-old man was diagnosed with ESCC after presenting with extensive disseminated skin nodules. Biopsy of the nodules showed metastatic ESCC. Cutaneous manifestations of esophageal neoplasia are very rare and are mainly described for esophageal adenocarcinoma EADC . Here we report a very uncommon case of extensive skin metastases of ESCC. Conclusion .